研究再次證實Benzalkonium Chloride與80%酒精含量的搓手液對甲型和乙型冠狀病毒的效果一致

研究再次證實Benzalkonium Chloride與80%酒精含量的搓手液對甲型和乙型冠狀病毒的效果一致

20239月,Brandon L. HerdtLuisa A. Ikner發表了一份搓手液有效成分(Benzalkonium Chloride80% 酒精)對甲型(SARS-CoV-2USA-WA1/2020分離株)和乙型(HCoV-229E)冠狀病毒的滅活動力,發現所有搓手液都能夠在15秒內對2種病毒株產生99.99%的殺菌效果,而病毒衰減速率和之前的幾個研究報告非常相似,進一步確認了Herdt等人(2021)、Chin等人(2020)、Ogilvie等人(2020)、Ijaz等人(2020)和Saknimit等人(1988)的發現,即商業BAK手部衛生配方和乙醇配方使冠狀病毒滅活。

Hand hygiene is critical to lower the potential for the spread of SARS-CoV-2 and other infectious agents by direct contact. When running water and soap are not available for hand hygiene, ethanol-based or Benzalkonium Chloride-based hand sanitizers are currently the recommended standard of care.  Recently published data showed comparable in vitro effectiveness of benzalkonium chloride (BAK)-based and ethanol-based hand sanitizers.  This paper found similar inactivation kinetics against human coronavirus HCoV-229E (genus Alphacoronavirus) concurrently with SARS-CoV-2, and Isolate USA-WA1/2020 (genus Betacoronavirus) as reported in previous reports by  Herdt et al. (2021) , Chin et al. (2020) , Ogilvie et al. (2020) , Ijaz et al. (2020), and Saknimit et al.

報告來源:

Inactivation kinetics of benzalkonium chloride and ethanol-based hand sanitizers against a betacoronavirus and an alphacoronavirus

苯扎氯銨和乙醇基洗手液對乙型冠狀病毒和甲型冠狀病毒的滅活動力學

By Brandon L. Herdt, Luisa A. Ikner

Infection Prevention in Practice, Volume 5, Issue 3, September 2023, 100293

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